Intra Cytoplasmic Sperm Injection (ICSI) is a procedure performed during in vitro fertilization (IVF) if there is concern about the sperm's ability to fertilize eggs. Some common reasons to perform ICSI are a low sperm count or poor sperm quality. The ICSI procedure involves taking the retrieved eggs and then inseminating each one within the laboratory by direct injection of a single sperm into each egg.

The availability of this Intra-Cytoplasmic Sperm Injection (ICSI) technique means that men whose sperm previously were too weak or too few to fertilize by conventional in vitro fertilization (IVF) methods, should have a much higher chance of fertilizing their partner's eggs. The fertilization rate per egg using ICSI is about 70%, the fertilization rate per infertile couple is over 99% if the partner has adequate eggs. This rate is very similar to IVF with normal sperm.

For more information on the IVF process, please read from some of these sources:

American Society for Reproductive Medicine

Resolve: The National Infertility Association